Biological reactive intermediates VI

chemical and biological mechanisms in susceptibility to and prevention of environmental diseases
  • 728 Pages
  • 4.31 MB
  • 6557 Downloads
  • English

Kluwer Academic/Plenum Publishers , New York
Biochemical toxicology -- Congresses, Environmental toxicology -- Congresses, Pollutants -- Structure-activity relationships -- Congresses, Toxicology -- methods -- Congresses, Biotransformation -- Congresses, Environmental Illness -- etiology -- Congresses, Environmental Illness -- prevention & control -- Congresses, Environmental Pollutants -- toxicity -- Congresses, Structure-Activity Relationship -- Congr
Other titlesBiological reactive intermediates six., Biological reactive intermediates 6.
Statementedited by Patrick M. Dansette ... [et al.].
GenreCongresses.
SeriesAdvances in experimental medicine and biology -- v. 500.
ContributionsDansette, Patrick M., International Symposium on Biological Reactive Intermediates (6th : 2000 : Université René Descartes)
The Physical Object
Paginationxv, 728 p. :
ID Numbers
Open LibraryOL18171441M
ISBN 100306466597
LC Control Number2001038407

Biological Reactive Intermediates Vi Sequestration of Biological Reactive Intermediates by Trapping as Covalent Enzyme-Intermediate Complex. Pages Biological Reactive Intermediates Vi Book Subtitle Chemical and Biological Mechanisms in Susceptibility to.

Biological Reactive Intermediates VI Mutagenicity and Carcinogenicity of Biological Reactive Intermediate’s Derived from a “Non-Genotoxic” Carcinogen. Chromosome Damage from Biological Reactive Intermediates of Benzene and 1,3-Butadiene in Leukemia. Martyn T. Smith. The papers that comprise this volume were submitted by world class scientists who were in attendance at The Symposium on Biological Reactive Intermediates VI.

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Witmer. Get this from a library. Biological reactive intermediates VI: chemical and biological mechanisms in susceptibility to and prevention of environmental disease. [Patrick M Dansette;] -- This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, i.e., toxic and carcinogenic effects, which.

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Jollow,Biological reactive intermediates VI book at Book Depository with free delivery worldwide. Get this from a library. Biological reactive intermediates V: basic mechanistic research in toxicology and human risk assessment. [Robert Snyder;] -- This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, i.e., toxic and carcinogenic effects, which.

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Abstract. Toxicity of drug candidates accounts for a significant portion of attrition during exploratory development. One common mode of toxicity is the formation of electrophilic reactive metabolites, which manifest their toxicity by covalent binding to nucleophilic groups present in vital cellular proteins and nucleic acids (1–2).Cited by: Similar mechanisms are likely to operate during the reduction of Cr(VI) in biological environment rich in reactive C-H bonds, including the oxidative DNA damage by Cr(V) intermediates.

View Show. A fluctuation test using Salmonella typhimurium strain has been used in an experimental protocol to assess biological effects of interactions between chromium (VI), such as K2CrO4, and two. Explains the role of reactive intermediates in biological systems as well as in environmental remediation With its clear and systematic approach, this book examined the broad range of reactive intermediate that can be generated in biological environments, detailing the fundamental properties of each reactive intermediate.

Readers gain a contemporary understanding of how these intermediates. Gas Mask Hood Assembly Chemical Biological Accessory $ The blood-brain barrier serves to protect the brain from toxic substances whilst simultaneously allowing access to essential nutrients and chemical signals.

At the interface between brain and body, knowledge of the blood-brain barrier forms an essential component in the complete understanding of a large proportion of medical disciplines. Author(s): Dansette,Patrick M; International Symposium on Biological Reactive Intermediates,(6th: Université René Descartes) Title(s): Biological reactive intermediates VI: chemical and biological mechanisms in susceptibility to and prevention of environmental diseases/ edited.

In chemistry a reactive intermediate is a short-lived high energy highly reactive molecule. When generated in a chemical reaction it will quickly convert into a more stable molecule. Only in exceptional cases these compounds can be isolated and stored. Reactive intermediates help explain how a chemical reaction takes place.

Purchase Biological Basis of Detoxication - 1st Edition. Print Book & E-Book. ISBNBook Edition: 1. Using the electrochemical method and layer-by-layer formation of interacting cytochrome P system components and DNA it could be shown that reactive intermediates were formed which could complex with and damage the DNA (Krishnan et al., ; So et al., ; So et al., ).

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Explains the role of reactive intermediates in biological systems as well as in environmental remediation. With its clear and systematic approach, this book examined the broad range of reactive intermediate that can be generated in biological environments, detailing.

@article{osti_, title = {Reaction of chromium(VI) with hydrogen peroxide in the presence of glutathione: Reactive intermediates and resulting DNA damage}, author = {Aiyar, J and Berkovits, H J and Wetterhahn, K E and Floyd, R A}, abstractNote = {The reaction of chromium(VI) with hydrogen peroxide was studied in the presence of glutathione.

In: Biological Reactive Intermediates IV Molecular and Cellular Effects and Their Impact on Human Health, DJ Jollow, R Snyder, IG Sipes, eds, Plenum Press, New York, ppRaucy JL, Lasker JM, Kraner JC, Salazar DE, Lieber CS, Corcoran GB: Induction of PIIE1 in the obese overfed rat.

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